Mechanism of cell death induced by the novel enzyme-prodrug combination, nitroreductase/CB1954, and identification of synergism with 5-fluorouracil. [electronic resource]
Producer: 20031023Description: 944-50 p. digitalISSN:- 0007-0920
- Adenoviridae
- Antimetabolites, Antineoplastic -- pharmacology
- Apoptosis -- drug effects
- Aziridines -- pharmacology
- Blotting, Western
- Caspases -- drug effects
- Drug Synergism
- Enzyme Inhibitors -- pharmacology
- Female
- Flow Cytometry
- Fluorouracil -- pharmacology
- Gene Transfer Techniques
- Genetic Therapy -- methods
- Genetic Vectors
- Humans
- Nitroreductases -- genetics
- Ovarian Neoplasms -- drug therapy
- Prodrugs -- pharmacology
- Tumor Cells, Cultured
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Publication Type: Journal Article
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