Resistance to indomethacin-induced down-regulation of hepatic cytochrome P450 enzymes in the mice with non-functional Toll-like receptor 4. [electronic resource]
Producer: 20040430Description: 349-56 p. digitalISSN:- 0168-8278
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- pharmacology
- Aryl Hydrocarbon Hydroxylases -- metabolism
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- metabolism
- Down-Regulation
- Drug Resistance
- Endotoxemia -- chemically induced
- Enzyme Activation -- drug effects
- Indomethacin -- pharmacology
- Lipopolysaccharides -- pharmacology
- Liver -- enzymology
- Male
- Membrane Glycoproteins -- metabolism
- Membrane Proteins -- metabolism
- Mice
- Mice, Inbred C3H
- Mixed Function Oxygenases -- antagonists & inhibitors
- Peptidoglycan -- pharmacology
- Receptors, Cell Surface -- metabolism
- Toll-Like Receptors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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