Phosphatidylinositol 3'-kinase is required for growth of mast cells expressing the kit catalytic domain mutant. [electronic resource]
Producer: 20030923Description: 4412-9 p. digitalISSN:- 0008-5472
- Androstadienes -- pharmacology
- Animals
- COS Cells
- Catalytic Domain
- Cell Division -- drug effects
- Cell Transformation, Neoplastic -- metabolism
- Chlorocebus aethiops
- Enzyme Activation
- Enzyme Inhibitors -- pharmacology
- Female
- Mast Cells -- cytology
- Mast-Cell Sarcoma -- enzymology
- Mice
- Mice, Inbred DBA
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- Phosphorylation
- Proto-Oncogene Proteins c-kit -- genetics
- Signal Transduction -- genetics
- Stem Cell Factor -- pharmacology
- Transfection
- Wortmannin
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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