Dendritic cells engineered to express the Flt3 ligand stimulate type I immune response, and induce enhanced cytoxic T and natural killer cell cytotoxicities and antitumor immunity. [electronic resource]
Producer: 20040709Description: 668-80 p. digitalISSN:- 1099-498X
- Adenoviridae -- genetics
- Adjuvants, Immunologic -- metabolism
- Animals
- Cancer Vaccines
- Cell Line, Tumor
- Cell Movement -- physiology
- Chemokines -- metabolism
- Cytokines -- metabolism
- Dendritic Cells -- immunology
- Female
- Humans
- Immune System -- physiology
- Killer Cells, Natural -- immunology
- Membrane Proteins -- genetics
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Neoplasms -- immunology
- Survival Rate
- T-Lymphocytes -- cytology
- T-Lymphocytes, Cytotoxic -- immunology
- Transgenes
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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