Inhibition of C5a-induced inflammation with preserved C5b-9-mediated bactericidal activity in a human whole blood model of meningococcal sepsis. [electronic resource]
Producer: 20040105Description: 3702-10 p. digitalISSN:- 0006-4971
- Antibodies, Monoclonal -- pharmacology
- Blood -- microbiology
- Complement Activation -- drug effects
- Complement C5a -- antagonists & inhibitors
- Complement Membrane Attack Complex -- immunology
- Granulocytes -- metabolism
- Humans
- Inflammation -- drug therapy
- Macrophage-1 Antigen -- biosynthesis
- Meningococcal Infections -- drug therapy
- Models, Biological
- Monocytes -- metabolism
- Neisseria meningitidis -- drug effects
- Receptors, Fc -- biosynthesis
- Respiratory Burst -- drug effects
- Sepsis -- drug therapy
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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