Prostaglandin E2 activates the histaminergic system via the EP4 receptor to induce wakefulness in rats. [electronic resource]
Producer: 20030807Description: 5975-83 p. digitalISSN:- 1529-2401
- Animals
- Dinoprostone -- pharmacology
- Dose-Response Relationship, Drug
- Frontal Lobe -- drug effects
- Histamine -- analysis
- Histidine Decarboxylase -- genetics
- Hypothalamic Area, Lateral -- cytology
- Hypothalamus -- drug effects
- Male
- Methyl Ethers -- pharmacology
- Microdialysis
- Neurons -- cytology
- Perfusion
- Preoptic Area -- drug effects
- RNA, Messenger -- metabolism
- Rats
- Rats, Sprague-Dawley
- Receptors, Prostaglandin E -- agonists
- Receptors, Prostaglandin E, EP4 Subtype
- Wakefulness -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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