Anterograde delivery of brain-derived neurotrophic factor to striatum via nigral transduction of recombinant adeno-associated virus increases neuronal death but promotes neurogenic response following stroke. [electronic resource]
Producer: 20030924Description: 2667-78 p. digitalISSN:- 0953-816X
- Analysis of Variance
- Animals
- Behavior, Animal
- Brain-Derived Neurotrophic Factor -- genetics
- Bromodeoxyuridine -- pharmacokinetics
- Cell Count
- Cell Death
- Cell Size -- physiology
- Choline O-Acetyltransferase -- metabolism
- Corpus Striatum -- metabolism
- Dependovirus -- genetics
- Disease Models, Animal
- Doublecortin Domain Proteins
- Doublecortin Protein
- ELAV Proteins
- Electroencephalography -- instrumentation
- Enzyme Inhibitors -- toxicity
- Enzyme-Linked Immunosorbent Assay
- Green Fluorescent Proteins
- Homeodomain Proteins -- metabolism
- Immunohistochemistry -- methods
- Infarction, Middle Cerebral Artery -- genetics
- Luminescent Proteins -- metabolism
- Male
- Microscopy, Confocal -- instrumentation
- Microtubule-Associated Proteins
- Nerve Tissue Proteins -- metabolism
- Neurons -- metabolism
- Neuropeptide Y -- metabolism
- Neuropeptides -- metabolism
- Parvalbumins -- metabolism
- RNA-Binding Proteins -- metabolism
- Radiation-Sensitizing Agents -- pharmacokinetics
- Rats
- Rats, Wistar
- Stroke -- pathology
- Substantia Nigra -- metabolism
- Transduction, Genetic -- methods
- alpha-Methyltyrosine -- toxicity
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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