Adenovirus-mediated heat-activated antisense Ku70 expression radiosensitizes tumor cells in vitro and in vivo. [electronic resource]
Producer: 20030728Description: 3268-74 p. digitalISSN:- 0008-5472
- Adenocarcinoma -- pathology
- Animals
- Antigens, Nuclear -- genetics
- Brain Neoplasms -- pathology
- Carcinoma, Squamous Cell -- pathology
- Combined Modality Therapy
- DNA Helicases
- DNA-Activated Protein Kinase
- DNA-Binding Proteins -- antagonists & inhibitors
- Feasibility Studies
- Female
- Fibrosarcoma -- pathology
- Gamma Rays
- Gene Expression Regulation, Neoplastic
- Genes, Reporter
- Genetic Therapy -- methods
- Genetic Vectors -- genetics
- Glioma -- pathology
- Green Fluorescent Proteins
- HSP70 Heat-Shock Proteins -- genetics
- Hot Temperature
- Humans
- Ku Autoantigen
- Luminescent Proteins -- biosynthesis
- Male
- Mastadenovirus -- genetics
- Mice
- Mice, Inbred C3H
- Neoplasm Proteins -- antagonists & inhibitors
- Nuclear Proteins
- Oligodeoxyribonucleotides, Antisense -- genetics
- Promoter Regions, Genetic
- Prostatic Neoplasms -- pathology
- Protein Serine-Threonine Kinases -- physiology
- Radiation Tolerance -- physiology
- Rats
- Transfection
- Tumor Cells, Cultured -- radiation effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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