Curcumin (diferuloylmethane) down-regulates cigarette smoke-induced NF-kappaB activation through inhibition of IkappaBalpha kinase in human lung epithelial cells: correlation with suppression of COX-2, MMP-9 and cyclin D1. [electronic resource]
Producer: 20030822Description: 1269-79 p. digitalISSN:- 0143-3334
- Antineoplastic Agents -- pharmacology
- Blotting, Western
- Carcinoma, Non-Small-Cell Lung -- metabolism
- Cells, Cultured
- Curcumin -- pharmacology
- Cyclin D1 -- metabolism
- Cyclooxygenase 2
- DNA Primers -- chemistry
- Down-Regulation -- drug effects
- Epithelial Cells -- drug effects
- Humans
- I-kappa B Kinase
- Isoenzymes -- metabolism
- Luciferases -- metabolism
- Lung Neoplasms -- metabolism
- Matrix Metalloproteinase 9 -- metabolism
- Membrane Proteins
- NF-kappa B -- metabolism
- Phosphorylation
- Prostaglandin-Endoperoxide Synthases -- metabolism
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- RNA, Messenger -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Smoking -- adverse effects
- Transfection
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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