Utilization of a beta-aminophosphotyrosyl mimetic in the design and synthesis of macrocyclic Grb2 SH2 domain-binding peptides. [electronic resource]
Producer: 20030715Description: 2621-30 p. digitalISSN:- 0022-2623
- Adaptor Proteins, Signal Transducing
- Cell Line
- Crystallography, X-Ray
- Cyclization
- Drug Design
- GRB2 Adaptor Protein
- Humans
- Ligands
- Models, Molecular
- Molecular Conformation
- Molecular Mimicry
- Peptides, Cyclic -- chemical synthesis
- Phosphotyrosine -- chemistry
- Proteins -- metabolism
- Structure-Activity Relationship
- src Homology Domains
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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