Con A activates an Akt/PKB dependent survival mechanism to modulate TCR induced cell death in double positive thymocytes. [electronic resource]
Producer: 20030627Description: 1013-23 p. digitalISSN:- 0161-5890
- Animals
- Antibodies -- pharmacology
- Apoptosis
- CD4-Positive T-Lymphocytes -- classification
- CD8-Positive T-Lymphocytes -- classification
- Carrier Proteins -- metabolism
- Cell Survival
- Concanavalin A -- pharmacology
- Enzyme Activation
- Mice
- Mice, Inbred BALB C
- Mice, Knockout
- Organ Culture Techniques
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoprotein Phosphatases -- antagonists & inhibitors
- Phosphorylation
- Protein Serine-Threonine Kinases
- Proto-Oncogene Proteins -- physiology
- Proto-Oncogene Proteins c-akt
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Receptor-CD3 Complex, Antigen, T-Cell -- immunology
- Signal Transduction
- T-Lymphocyte Subsets -- classification
- Thymus Gland -- cytology
- bcl-Associated Death Protein
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Publication Type: Journal Article
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