Diacerein reduces the level of cartilage chondrocyte DNA fragmentation and death in experimental dog osteoarthritic cartilage at the same time that it inhibits caspase-3 and inducible nitric oxide synthase. [electronic resource]
Producer: 20030808Description: 171-7 p. digitalISSN:- 0392-856X
- Animals
- Anthraquinones -- pharmacology
- Anti-Inflammatory Agents, Non-Steroidal -- pharmacology
- Cartilage -- drug effects
- Caspase 3
- Caspase Inhibitors
- Caspases -- immunology
- Cells, Cultured
- Chondrocytes -- drug effects
- DNA Fragmentation -- drug effects
- Dogs
- Enzyme Inhibitors -- pharmacology
- In Situ Nick-End Labeling
- Mixed Function Oxygenases -- pharmacology
- Nitric Oxide Synthase -- antagonists & inhibitors
- Nitric Oxide Synthase Type II
- Osteoarthritis, Knee -- drug therapy
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.