More potent inhibition of human CYP2A6 than mouse CYP2A5 enzyme activities by derivatives of phenylethylamine and benzaldehyde. [electronic resource]
Producer: 20040129Description: 529-39 p. digitalISSN:- 0049-8254
- Animals
- Aryl Hydrocarbon Hydroxylases -- antagonists & inhibitors
- Benzaldehydes -- chemistry
- Binding, Competitive
- Cytochrome P-450 CYP2A6
- Cytochrome P450 Family 2
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- pharmacology
- Humans
- Inhibitory Concentration 50
- Kinetics
- Mice
- Microsomes, Liver -- enzymology
- Mixed Function Oxygenases -- antagonists & inhibitors
- Phenethylamines -- chemistry
- Regression Analysis
- Structure-Activity Relationship
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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