Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells. [electronic resource]
Producer: 20030530Description: 1086-96 p. digitalISSN:- 0270-9139
- Antineoplastic Agents -- pharmacology
- CDC2-CDC28 Kinases
- Carcinoma, Hepatocellular
- Cell Cycle Proteins -- genetics
- Chromans -- pharmacology
- Cyclin E -- genetics
- Cyclin-Dependent Kinase 2
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclin-Dependent Kinase Inhibitor p27
- Cyclin-Dependent Kinases -- metabolism
- Cyclins -- genetics
- Down-Regulation
- Drug Resistance, Neoplasm
- G1 Phase -- physiology
- Gene Expression Regulation, Neoplastic
- Humans
- Liver Neoplasms
- Protein Binding
- Protein Serine-Threonine Kinases -- metabolism
- RNA, Messenger -- analysis
- S-Phase Kinase-Associated Proteins
- Thiazoles -- pharmacology
- Thiazolidinediones
- Troglitazone
- Tumor Cells, Cultured
- Tumor Suppressor Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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