Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase. [electronic resource]
Producer: 20030820Description: 24233-41 p. digitalISSN:- 0021-9258
- Active Transport, Cell Nucleus
- Dose-Response Relationship, Drug
- Enzyme Precursors -- metabolism
- Humans
- Hydrogen Peroxide -- pharmacology
- I-kappa B Proteins -- metabolism
- Intracellular Signaling Peptides and Proteins
- Kinetics
- NF-kappa B -- drug effects
- Phosphorylation -- drug effects
- Protein-Tyrosine Kinases -- metabolism
- Serine -- metabolism
- Syk Kinase
- Transcription Factor RelA
- Tumor Cells, Cultured
- Tumor Necrosis Factor-alpha -- pharmacology
- Tyrosine -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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