The small GTPase Rap1 is activated by turbulence and is involved in integrin [alpha]IIb[beta]3-mediated cell adhesion in human megakaryocytes. [electronic resource]
Producer: 20030821Description: 22412-7 p. digitalISSN:- 0021-9258
- Blood Platelets -- physiology
- Cell Adhesion -- drug effects
- Cell Line
- Chelating Agents -- pharmacology
- Egtazic Acid -- analogs & derivatives
- Enzyme Inhibitors -- pharmacology
- Fibrinogen -- physiology
- Humans
- Jurkat Cells
- K562 Cells
- Megakaryocytes -- physiology
- Platelet Glycoprotein GPIIb-IIIa Complex -- physiology
- Protein Kinase C -- antagonists & inhibitors
- Recombinant Proteins -- metabolism
- Signal Transduction
- Stress, Mechanical
- Transfection
- Tumor Cells, Cultured
- rap1 GTP-Binding Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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