Suppression of human prostate cancer cell growth by beta-lapachone via down-regulation of pRB phosphorylation and induction of Cdk inhibitor p21(WAF1/CIP1). [electronic resource]
Producer: 20040112Description: 223-9 p. digitalISSN:- 1225-8687
- Antineoplastic Agents -- pharmacology
- Apoptosis
- CDC2-CDC28 Kinases -- metabolism
- Cell Cycle Proteins -- metabolism
- Cell Division
- Cell Line, Tumor
- Cyclin-Dependent Kinase 2
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclin-Dependent Kinases -- metabolism
- Cyclins -- biosynthesis
- DNA-Binding Proteins
- Down-Regulation
- E2F Transcription Factors
- E2F1 Transcription Factor
- Humans
- Male
- Naphthoquinones -- pharmacology
- Phosphorylation
- Prostatic Neoplasms -- metabolism
- Retinoblastoma Protein -- metabolism
- Transcription Factors -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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