Poly(ADP-ribose) polymerase-1 activity promotes NF-kappaB-driven transcription and microglial activation: implication for neurodegenerative disorders. [electronic resource]
Producer: 20030514Description: 306-17 p. digitalISSN:- 0022-3042
- Animals
- Astrocytes -- cytology
- Cells, Cultured
- Coculture Techniques
- Corpus Striatum -- drug effects
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Excitatory Amino Acid Antagonists -- pharmacology
- Inflammation Mediators -- metabolism
- Interferon-gamma
- L-Lactate Dehydrogenase -- metabolism
- Lipopolysaccharides
- Microglia -- cytology
- Microinjections
- NF-kappa B -- metabolism
- Neurodegenerative Diseases -- chemically induced
- Neurons -- cytology
- Nitric Oxide Synthase -- metabolism
- Nitric Oxide Synthase Type II
- Poly Adenosine Diphosphate Ribose -- metabolism
- Poly(ADP-ribose) Polymerase Inhibitors
- Poly(ADP-ribose) Polymerases -- metabolism
- Rats
- Transcription, Genetic -- physiology
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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