Enzyme therapy of gaucher disease: clinical and biochemical changes during production of and tolerization for neutralizing antibodies. [electronic resource]
Producer: 20040130Description: 90-6 p. digitalISSN:- 1079-9796
- Alleles
- Antibodies -- blood
- Biomarkers -- blood
- Child
- Child, Preschool
- DNA Mutational Analysis
- Dose-Response Relationship, Drug
- Electrophoresis, Polyacrylamide Gel
- Enzyme-Linked Immunosorbent Assay
- Female
- Gaucher Disease -- blood
- Glucosylceramidase -- genetics
- Humans
- Immune Tolerance
- Immunoglobulin G -- blood
- Liver -- drug effects
- Mutation
- Neutralization Tests
- Polymerase Chain Reaction
- Spleen -- drug effects
- Time Factors
- Treatment Outcome
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Publication Type: Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.
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