A novel missense mutation in the gamma-glutamylcysteine synthetase catalytic subunit gene causes both decreased enzymatic activity and glutathione production. [electronic resource]
Producer: 20030912Description: 725-30 p. digitalISSN:- 0006-4971
- Amino Acid Substitution
- Animals
- Binding Sites
- Catalytic Domain -- genetics
- Cells, Cultured -- enzymology
- Codon -- genetics
- Fibroblasts -- enzymology
- Glutamate-Cysteine Ligase -- chemistry
- Glutathione -- biosynthesis
- Homozygote
- Humans
- Kinetics
- Mice
- Mice, Knockout
- Models, Molecular
- Mutation, Missense
- Protein Conformation
- Recombinant Fusion Proteins -- metabolism
- Structure-Activity Relationship
- Transfection
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.