Engineering exosite peptides for complete inhibition of factor VIIa using a protease switch with substrate phage. [electronic resource]
Producer: 20030722Description: 21823-30 p. digitalISSN:- 0021-9258
- Amino Acid Sequence
- Amino Acids -- chemistry
- Anticoagulants -- pharmacology
- Arginine -- chemistry
- Binding Sites
- Crystallography, X-Ray
- DNA -- metabolism
- Dose-Response Relationship, Drug
- Factor VIIa -- antagonists & inhibitors
- Humans
- Hydrogen-Ion Concentration
- Inhibitory Concentration 50
- Models, Biological
- Models, Molecular
- Molecular Sequence Data
- Peptide Library
- Peptides -- chemistry
- Protein Binding
- Protein Structure, Tertiary
- Prothrombin Time
- Thromboplastin -- chemistry
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Publication Type: Journal Article
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