Homology modelling of CYP2A6 based on the CYP2C5 crystallographic template: enzyme-substrate interactions and QSARs for binding affinity and inhibition. [electronic resource]
Producer: 20031120Description: 179-90 p. digitalISSN:- 0887-2333
- Amino Acid Sequence
- Aryl Hydrocarbon Hydroxylases -- chemistry
- Binding Sites
- Crystallography
- Cytochrome P-450 CYP2A6
- Cytochrome P-450 Enzyme System -- chemistry
- Cytochrome P450 Family 2
- Humans
- Kinetics
- Mixed Function Oxygenases -- chemistry
- Models, Molecular
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Quantitative Structure-Activity Relationship
- Sequence Alignment
- Sequence Homology
- Steroid 21-Hydroxylase -- chemistry
- Substrate Specificity
- Templates, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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