Use of a pharmacophore model to discover a new class of influenza endonuclease inhibitors. [electronic resource]
Producer: 20030502Description: 1153-64 p. digitalISSN:- 0022-2623
- Animals
- Antiviral Agents -- chemical synthesis
- Binding Sites
- Butyrates -- chemical synthesis
- Cell Line
- Combinatorial Chemistry Techniques
- DNA-Directed RNA Polymerases -- chemistry
- Databases, Factual
- Dogs
- Endonucleases -- antagonists & inhibitors
- Enzyme Inhibitors -- chemical synthesis
- Heterocyclic Compounds, 3-Ring -- chemical synthesis
- Heterocyclic Compounds, 4 or More Rings -- chemical synthesis
- Influenza A virus -- drug effects
- Influenza B virus -- drug effects
- Keto Acids -- chemical synthesis
- Models, Molecular
- Phthalimides -- chemical synthesis
- Protein Binding
- Structure-Activity Relationship
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Publication Type: Journal Article
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