Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. [electronic resource]
Producer: 20030707Description: 19341-6 p. digitalISSN:- 0021-9258
- Binding Sites
- DNA -- biosynthesis
- DNA Damage
- DNA-Directed DNA Polymerase -- chemistry
- Escherichia coli -- genetics
- Gene Expression
- Gene Library
- Humans
- Kinetics
- Models, Molecular
- Mutagenesis, Site-Directed
- Polymerase Chain Reaction
- Purines -- metabolism
- Pyrimidines -- metabolism
- Saccharomyces cerevisiae -- genetics
- Structure-Activity Relationship
- Templates, Genetic
- Transfection
- Tyrosine
- Ultraviolet Rays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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