The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents. [electronic resource]
Producer: 20031003Description: 1136-44 p. digitalISSN:- 1078-0432
- Active Transport, Cell Nucleus
- Adenoviridae -- genetics
- Antineoplastic Agents -- pharmacology
- Apoptosis
- Blotting, Western
- Boronic Acids -- pharmacology
- Bortezomib
- Cell Division
- Cell Nucleus -- metabolism
- Cell Survival
- Cysteine Endopeptidases
- Cytosol -- metabolism
- Dose-Response Relationship, Drug
- Genes, Dominant
- Humans
- I-kappa B Proteins -- metabolism
- Melphalan -- pharmacology
- Microscopy, Fluorescence
- Multienzyme Complexes -- antagonists & inhibitors
- Multiple Myeloma -- metabolism
- NF-KappaB Inhibitor alpha
- NF-kappa B -- metabolism
- Phosphorylation
- Proteasome Endopeptidase Complex
- Pyrazines -- pharmacology
- Tetrazolium Salts -- pharmacology
- Thiazoles -- pharmacology
- Time Factors
- Transfection
- Tumor Cells, Cultured
- Ubiquitin -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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