Cutting edge: Mycobacterium tuberculosis blocks Ca2+ signaling and phagosome maturation in human macrophages via specific inhibition of sphingosine kinase. [electronic resource]
Producer: 20030625Description: 2811-5 p. digitalISSN:- 0022-1767
- Animals
- CHO Cells
- Calcium -- metabolism
- Calcium Signaling -- immunology
- Cell Fractionation
- Cricetinae
- Enzyme Activation
- Humans
- Lysophospholipids
- Macrophage-1 Antigen -- physiology
- Macrophages -- enzymology
- Mycobacterium tuberculosis -- growth & development
- Phagocytosis -- immunology
- Phagosomes -- enzymology
- Phosphotransferases (Alcohol Group Acceptor) -- antagonists & inhibitors
- Sphingosine -- analogs & derivatives
- Tuberculosis Vaccines -- pharmacology
- Vaccines, Inactivated -- pharmacology
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Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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