8-hydroxydeoxyguanosine causes death of human leukemia cells deficient in 8-oxoguanine glycosylase 1 activity by inducing apoptosis. [electronic resource]
Producer: 20040217Description: 290-9 p. digitalISSN:- 1541-7786
- 8-Hydroxy-2'-Deoxyguanosine
- Apoptosis -- drug effects
- Cell Division -- drug effects
- Cell Line, Tumor
- DNA -- chemistry
- DNA-Formamidopyrimidine Glycosylase -- deficiency
- Deoxyguanosine -- analogs & derivatives
- Escherichia coli Proteins -- metabolism
- Fas Ligand Protein
- Guanine -- analogs & derivatives
- Humans
- Leukemia -- enzymology
- Membrane Glycoproteins -- metabolism
- Reactive Oxygen Species -- metabolism
- fas Receptor -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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