Activated c-Met signals through PI3K with dramatic effects on cytoskeletal functions in small cell lung cancer. [electronic resource]
Producer: 20030513Description: 539-53 p. digitalISSN:- 1582-1838
- Adaptor Proteins, Signal Transducing
- Benzoquinones
- Carcinoma, Small Cell -- enzymology
- Cell Movement -- drug effects
- Cell Survival -- drug effects
- Chromones -- pharmacology
- Cytoskeleton -- metabolism
- Dose-Response Relationship, Drug
- Drosophila Proteins
- Enzyme Inhibitors -- pharmacology
- Growth Substances -- pharmacology
- Humans
- Lactams, Macrocyclic
- Lung Neoplasms -- enzymology
- Microtubule-Associated Proteins -- antagonists & inhibitors
- Morpholines -- pharmacology
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- Phosphoproteins -- antagonists & inhibitors
- Phosphorylation
- Protein Binding -- drug effects
- Protein Serine-Threonine Kinases
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-akt
- Quinones -- pharmacology
- Serine -- metabolism
- Signal Transduction -- drug effects
- Tumor Cells, Cultured
- Tyrosine -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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