Interferon-gamma stimulates the expression of the inducible cAMP early repressor in macrophages through the activation of casein kinase 2. A potentially novel pathway for interferon-gamma-mediated inhibition of gene transcription. [electronic resource]
Producer: 20030625Description: 17741-51 p. digitalISSN:- 0021-9258
- 8-Bromo Cyclic Adenosine Monophosphate -- metabolism
- Animals
- Apigenin
- Blotting, Western
- Calcimycin -- pharmacology
- Calcium -- metabolism
- Casein Kinase II
- Cell Line
- Cloning, Molecular
- Colforsin -- pharmacology
- Cyclic AMP -- metabolism
- Cyclic AMP Response Element Modulator
- Cyclic AMP-Dependent Protein Kinase Type II
- Cyclic AMP-Dependent Protein Kinases -- antagonists & inhibitors
- DNA -- metabolism
- DNA-Binding Proteins -- metabolism
- Electrophoresis, Polyacrylamide Gel
- Enzyme Activation
- Enzyme Inhibitors -- pharmacology
- Flavonoids -- metabolism
- Gene Expression Regulation, Enzymologic
- Genetic Vectors
- Imidazoles -- pharmacology
- Indoles -- pharmacology
- Interferon-gamma -- metabolism
- Macrophages -- enzymology
- Maleimides -- pharmacology
- Mice
- Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- Phosphorylation
- Protein Binding
- Protein Kinase C -- antagonists & inhibitors
- Protein Serine-Threonine Kinases -- metabolism
- Pyridines -- pharmacology
- RNA, Messenger -- metabolism
- Repressor Proteins
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction
- Sulfonamides -- pharmacology
- Tetradecanoylphorbol Acetate -- pharmacology
- Thapsigargin -- pharmacology
- Time Factors
- Transcription, Genetic
- Transcriptional Activation
- Tyrphostins -- pharmacology
- p38 Mitogen-Activated Protein Kinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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