Differential requirements for JAK2 and TYK2 in T cell proliferation and IFN-gamma production induced by IL-12 alone or together with IL-18. [electronic resource]
Producer: 20030312Description: 243-51 p. digitalISSN:- 0014-2980
- Animals
- Cell Division -- drug effects
- Cell Line
- DNA-Binding Proteins -- metabolism
- Enzyme Activation -- drug effects
- Gene Expression Regulation -- drug effects
- Interferon-gamma -- metabolism
- Interleukin-12 -- pharmacology
- Interleukin-18 -- pharmacology
- Janus Kinase 2
- Mice
- Milk Proteins
- Protein-Tyrosine Kinases -- metabolism
- Proteins -- metabolism
- Proto-Oncogene Proteins
- STAT3 Transcription Factor
- STAT4 Transcription Factor
- STAT5 Transcription Factor
- T-Lymphocytes -- cytology
- TYK2 Kinase
- Trans-Activators -- metabolism
- Tyrphostins -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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