Fine-scale mapping at IGAD1 and genome-wide genetic linkage analysis implicate HLA-DQ/DR as a major susceptibility locus in selective IgA deficiency and common variable immunodeficiency. [electronic resource]
Producer: 20030521Description: 2765-75 p. digitalISSN:- 0022-1767
- Alleles
- Chromosome Mapping -- methods
- Common Variable Immunodeficiency -- genetics
- Female
- Genetic Markers -- immunology
- Genetic Predisposition to Disease -- genetics
- Genome, Human
- HLA-DQ Antigens -- biosynthesis
- HLA-DR Antigens -- biosynthesis
- Haplotypes -- immunology
- Histocompatibility Testing -- methods
- Homozygote
- Humans
- IgA Deficiency -- genetics
- Linkage Disequilibrium
- Male
- Nuclear Family
- Polymorphism, Single Nucleotide -- genetics
- Tandem Repeat Sequences -- immunology
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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