The novel synthetic immune response modifier R-848 (Resiquimod) shifts human allergen-specific CD4+ TH2 lymphocytes into IFN-gamma-producing cells. [electronic resource]
Producer: 20030325Description: 380-8 p. digitalISSN:- 0091-6749
- Adjuvants, Immunologic -- pharmacology
- Adult
- Allergens
- Ampicillin -- adverse effects
- Animals
- Antigens, Dermatophagoides -- immunology
- Arthropod Proteins
- Cell Line
- Cysteine Endopeptidases
- Cytokines -- biosynthesis
- Drug Hypersensitivity -- immunology
- Humans
- Hypersensitivity, Immediate -- immunology
- Imidazoles -- pharmacology
- In Vitro Techniques
- Interferon-gamma -- biosynthesis
- Models, Immunological
- T-Lymphocyte Subsets -- drug effects
- Th1 Cells -- drug effects
- Th2 Cells -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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