Cephalosporin prodrugs of paclitaxel for immunologically specific activation by L-49-sFv-beta-lactamase fusion protein. [electronic resource]
Producer: 20030815Description: 539-42 p. digitalISSN:- 0960-894X
- Antineoplastic Agents, Phytogenic -- chemical synthesis
- Cephalosporins -- chemical synthesis
- Chromatography, High Pressure Liquid
- Cyclization
- Enzyme Inhibitors -- chemical synthesis
- Half-Life
- Humans
- Immunoglobulin G -- pharmacology
- In Vitro Techniques
- Indicators and Reagents
- Melanoma, Experimental -- drug therapy
- Paclitaxel -- analogs & derivatives
- Prodrugs -- chemical synthesis
- Recombinant Fusion Proteins -- chemical synthesis
- Structure-Activity Relationship
- Tumor Cells, Cultured
- beta-Lactamase Inhibitors
- beta-Lactamases -- pharmacology
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Publication Type: Journal Article
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