The ability of statins to inhibit bone resorption is directly related to their inhibitory effect on HMG-CoA reductase activity. [electronic resource]
Producer: 20030407Description: 88-96 p. digitalISSN:- 0884-0431
- Animals
- Bone Resorption -- enzymology
- Calcium -- metabolism
- Female
- Hydroxymethylglutaryl CoA Reductases -- metabolism
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- In Vitro Techniques
- Lovastatin -- pharmacology
- Male
- Osteoclasts -- drug effects
- Osteogenesis -- drug effects
- Parathyroidectomy
- Pravastatin -- pharmacology
- Protein Prenylation -- drug effects
- Pyridines -- pharmacology
- Rabbits
- Rats
- Rats, Sprague-Dawley
- Simvastatin -- pharmacology
- Thyroidectomy
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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