Low levels of glutathione peroxidase 1 activity in selenium-deficient mouse liver affect c-Jun N-terminal kinase activation and p53 phosphorylation on Ser-15 in pro-oxidant-induced aponecrosis. [electronic resource]
Producer: 20030423Description: 927-34 p. digitalISSN:- 0264-6021
- Animals
- DNA -- metabolism
- Enzyme Activation
- Glutathione Peroxidase -- genetics
- Herbicides -- pharmacology
- JNK Mitogen-Activated Protein Kinases
- Liver -- cytology
- Mice
- Mice, Knockout
- Mitogen-Activated Protein Kinases -- metabolism
- Necrosis
- Oxidants -- metabolism
- Paraquat -- pharmacology
- Phosphorylation
- Selenium -- deficiency
- Serine -- metabolism
- Tumor Suppressor Protein p53 -- metabolism
- Glutathione Peroxidase GPX1
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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