Therapeutic intervention in experimental allergic encephalomyelitis by administration of uric acid precursors. [electronic resource]
Producer: 20030128Description: 16303-8 p. digitalISSN:- 0027-8424
- Administration, Oral
- Animals
- Biotransformation
- Chromatography, High Pressure Liquid
- Drug Evaluation, Preclinical
- Encephalomyelitis, Autoimmune, Experimental -- drug therapy
- Enzyme Induction -- drug effects
- Enzyme Inhibitors -- pharmacology
- Female
- Humans
- Inosine -- pharmacokinetics
- Inosine Monophosphate -- pharmacokinetics
- Mice
- Molsidomine -- analogs & derivatives
- Monocytes -- drug effects
- Multiple Sclerosis -- metabolism
- Nitric Oxide Synthase -- biosynthesis
- Nitric Oxide Synthase Type II
- Oxidation-Reduction
- Oxidative Stress
- Oxonic Acid -- pharmacology
- Peroxynitrous Acid -- metabolism
- Urate Oxidase -- antagonists & inhibitors
- Uric Acid -- analogs & derivatives
- Xanthines -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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