Regulation of CYP2B6 and CYP3A expression by hydroxymethylglutaryl coenzyme A inhibitors in primary cultured human hepatocytes. [electronic resource]
Producer: 20030513Description: 1400-5 p. digitalISSN:- 0090-9556
- Animals
- Aryl Hydrocarbon Hydroxylases -- biosynthesis
- Cells, Cultured
- Cytochrome P-450 CYP2B6
- Cytochrome P-450 CYP3A
- Gene Expression Regulation, Enzymologic -- drug effects
- Hepatocytes -- cytology
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Male
- Oxidoreductases, N-Demethylating -- biosynthesis
- RNA, Messenger -- biosynthesis
- Rats
- Rats, Sprague-Dawley
- Species Specificity
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Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
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