Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia. [electronic resource]
Producer: 20030313Description: 1270-6 p. digitalISSN:- 0006-4971
- Arabinofuranosylcytosine Triphosphate -- metabolism
- Cell Survival
- Child
- Child, Preschool
- Cytarabine -- metabolism
- DCMP Deaminase -- genetics
- DNA-Binding Proteins -- genetics
- Deoxycytidine Kinase -- genetics
- Drug Resistance, Neoplasm -- genetics
- Equilibrative Nucleoside Transporter 1 -- genetics
- Female
- Gene Expression
- Gene Rearrangement
- Histone-Lysine N-Methyltransferase
- Humans
- Infant
- Male
- Myeloid-Lymphoid Leukemia Protein
- Oligonucleotide Array Sequence Analysis
- Polymerase Chain Reaction
- Precursor Cell Lymphoblastic Leukemia-Lymphoma -- drug therapy
- Proto-Oncogenes
- Pyrimidine Nucleotides -- genetics
- RNA, Messenger -- analysis
- Transcription Factors
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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