PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival. [electronic resource]
Producer: 20021209Description: 1079-88 p. digitalISSN:- 0270-9139
- Animals
- Carrier Proteins -- metabolism
- Cell Division -- physiology
- Cell Survival -- physiology
- Cells, Cultured
- Cyclin D1 -- metabolism
- DNA -- biosynthesis
- Enzyme Inhibitors -- pharmacology
- Epidermal Growth Factor -- pharmacology
- G1 Phase -- physiology
- Hepatocytes -- cytology
- Insulin -- metabolism
- Intracellular Signaling Peptides and Proteins
- MAP Kinase Kinase Kinase 1
- MAP Kinase Signaling System -- drug effects
- Male
- Mitogen-Activated Protein Kinases -- metabolism
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- Phosphoproteins -- metabolism
- Phosphorylation
- Protein Biosynthesis
- Protein Kinases -- metabolism
- Protein Serine-Threonine Kinases -- metabolism
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-akt
- Rats
- Rats, Sprague-Dawley
- S Phase -- physiology
- TOR Serine-Threonine Kinases
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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