The cytoplasmic C-terminus of the sulfonylurea receptor is important for KATP channel function but is not key for complex assembly or trafficking. [electronic resource]
Producer: 20021213Description: 5303-13 p. digitalISSN:- 0014-2956
- ATP-Binding Cassette Transporters
- Adenosine Diphosphate -- pharmacology
- Adenosine Triphosphate -- pharmacology
- Animals
- Biotinylation
- Cell Line
- Cell Membrane -- metabolism
- Cricetinae
- Diazoxide -- pharmacology
- Fluorescent Antibody Technique
- Glyburide -- pharmacokinetics
- Humans
- Kidney -- cytology
- Macromolecular Substances
- Mutagenesis, Site-Directed
- Patch-Clamp Techniques
- Potassium Channels -- drug effects
- Potassium Channels, Inwardly Rectifying -- drug effects
- Protein Binding -- physiology
- Protein Structure, Tertiary -- physiology
- Protein Transport -- physiology
- Receptors, Drug -- drug effects
- Sequence Deletion
- Structure-Activity Relationship
- Sulfonylurea Receptors
- Tolbutamide -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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