Muc4/sialomucin complex, the intramembrane ErbB2 ligand, induces specific phosphorylation of ErbB2 and enhances expression of p27(kip), but does not activate mitogen-activated kinase or protein kinaseB/Akt pathways. [electronic resource]
Producer: 20021114Description: 7524-32 p. digitalISSN:- 0950-9232
- Animals
- Cell Adhesion
- Cell Cycle Proteins -- genetics
- Cyclin-Dependent Kinase Inhibitor p27
- Enzyme Activation
- Gene Expression Regulation -- physiology
- Humans
- Ligands
- Mitogen-Activated Protein Kinases -- metabolism
- Mucin-4
- Mucins -- metabolism
- Phosphorylation
- Receptor, ErbB-2 -- metabolism
- Sialoglycoproteins -- metabolism
- Spodoptera
- Tumor Cells, Cultured
- Tumor Suppressor Proteins -- genetics
- Tyrosine -- metabolism
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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