Platelet glycoprotein IIb/IIIa receptor antagonist (abciximab) inhibited platelet activation and promoted skin flap survival after ischemia/reperfusion injury. [electronic resource]
Producer: 20021113Description: 50-5 p. digitalISSN:- 0022-4804
- Abciximab
- Adenosine Diphosphate -- pharmacology
- Animals
- Antibodies, Monoclonal -- administration & dosage
- Blood Platelets -- drug effects
- Dose-Response Relationship, Drug
- Endothelium, Vascular -- drug effects
- Immunoglobulin Fab Fragments -- administration & dosage
- Ischemia -- physiopathology
- Male
- P-Selectin -- metabolism
- Platelet Activation -- drug effects
- Platelet Aggregation -- drug effects
- Platelet Count
- Platelet Glycoprotein GPIIb-IIIa Complex -- antagonists & inhibitors
- Rats
- Rats, Inbred Lew
- Regional Blood Flow -- drug effects
- Reperfusion Injury -- physiopathology
- Skin -- blood supply
- Surgical Flaps -- physiology
- Time Factors
- Tissue Survival -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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