Signaling through NK cell-associated CD137 promotes both helper function for CD8+ cytolytic T cells and responsiveness to IL-2 but not cytolytic activity. [electronic resource]
Producer: 20021127Description: 4230-6 p. digitalISSN:- 0022-1767
- Adjuvants, Immunologic -- metabolism
- Animals
- Antigens, CD
- Cytotoxicity, Immunologic
- Female
- Growth Substances -- metabolism
- Injections, Intraperitoneal
- Injections, Subcutaneous
- Interleukin-2 -- metabolism
- Killer Cells, Natural -- immunology
- Leukemia L1210
- Lymphocyte Subsets -- immunology
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Mice, Knockout
- Mice, Transgenic
- Receptors, Interleukin-2 -- biosynthesis
- Receptors, Nerve Growth Factor -- administration & dosage
- Receptors, Tumor Necrosis Factor -- administration & dosage
- Signal Transduction -- immunology
- Solubility
- T-Lymphocytes, Cytotoxic -- cytology
- Tumor Cells, Cultured
- Tumor Necrosis Factor Receptor Superfamily, Member 9
- Up-Regulation -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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