Stimulation of peroxisome proliferator-activated receptors alpha and gamma blocks HIV-1 replication and TNFalpha production in acutely infected primary blood cells, chronically infected U1 cells, and alveolar macrophages from HIV-infected subjects. [electronic resource]
Producer: 20021010Description: 1-10 p. digitalISSN:- 1525-4135
- Acquired Immunodeficiency Syndrome -- drug therapy
- Anti-HIV Agents -- pharmacology
- Cell Line
- Chromans -- pharmacology
- Fenofibrate -- pharmacology
- HIV-1 -- drug effects
- Humans
- Leukocytes, Mononuclear -- immunology
- Macrophages, Alveolar -- immunology
- Prostaglandin D2 -- analogs & derivatives
- Receptors, Cytoplasmic and Nuclear -- physiology
- Rosiglitazone
- Thiazoles -- pharmacology
- Thiazolidinediones
- Transcription Factors -- physiology
- Troglitazone
- Tumor Necrosis Factor-alpha -- biosynthesis
- Virus Replication -- drug effects
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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