Mechanism of antiandrogen action: key role of hsp90 in conformational change and transcriptional activity of the androgen receptor. [electronic resource]
Producer: 20021119Description: 11824-31 p. digitalISSN:- 0006-2960
- Active Transport, Cell Nucleus -- drug effects
- Androgen Antagonists -- chemistry
- Animals
- Benzoquinones
- COS Cells
- Cell Line
- Cell Nucleus -- chemistry
- Endopeptidases
- Green Fluorescent Proteins
- HSP90 Heat-Shock Proteins -- antagonists & inhibitors
- Humans
- Hydrolysis
- Kinetics
- Lactams, Macrocyclic
- Luminescent Proteins -- genetics
- Microscopy, Fluorescence
- Plasmids
- Protein Conformation
- Quinones -- pharmacology
- Receptors, Androgen -- chemistry
- Trans-Activators -- chemistry
- Transfection
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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