A cell-based reporter gene assay for determining induction of CYP3A4 in a high-volume system. [electronic resource]
Producer: 20021021Description: 412-23 p. digitalISSN:- 0022-3565
- Base Sequence
- Blotting, Northern
- Cell Line, Transformed
- Cell Survival -- physiology
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- biosynthesis
- DNA Primers
- Enzyme Induction
- Genes, Reporter
- Hepatocytes -- metabolism
- Humans
- Liver -- metabolism
- Lovastatin -- analogs & derivatives
- Luciferases -- genetics
- Mifepristone -- pharmacology
- Mixed Function Oxygenases -- biosynthesis
- Omeprazole -- pharmacology
- Polychlorinated Dibenzodioxins -- pharmacology
- Pregnane X Receptor
- RNA, Messenger -- genetics
- Receptors, Cytoplasmic and Nuclear -- genetics
- Receptors, Steroid -- genetics
- Recombinant Fusion Proteins -- biosynthesis
- Reverse Transcriptase Polymerase Chain Reaction
- Rifampin -- pharmacology
- Transcription, Genetic -- drug effects
- Transfection -- methods
No physical items for this record
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
There are no comments on this title.
Log in to your account to post a comment.