Methylation of L-trans-2,4-pyrrolidine dicarboxylate converts the glutamate transport inhibitor from a substrate to a non-substrate inhibitor. [electronic resource]
Producer: 20030304Description: 3509-15 p. digitalISSN:- 0968-0896
- Amino Acid Transport System X-AG -- drug effects
- Animals
- Carboxylic Acids -- chemistry
- Computational Biology
- Cyclization
- Dicarboxylic Acids
- Excitatory Amino Acid Transporter 2 -- chemistry
- In Vitro Techniques
- Indicators and Reagents
- Kinetics
- Methylation
- Models, Chemical
- Models, Molecular
- Molecular Conformation
- Prosencephalon -- metabolism
- Pyrrolidines -- chemistry
- Rats
- Synaptosomes -- drug effects
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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