Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer. [electronic resource]
Producer: 20021003Description: 4968-76 p. digitalISSN:- 0008-5472
- Adenoviruses, Human -- genetics
- Aged
- Aged, 80 and over
- Biopsy
- Cytosine Deaminase
- DNA, Viral -- blood
- Flucytosine -- pharmacokinetics
- Ganciclovir -- pharmacokinetics
- Genetic Therapy -- adverse effects
- Herpesvirus 1, Human -- enzymology
- Humans
- Male
- Middle Aged
- Neoplasm Recurrence, Local -- blood
- Nucleoside Deaminases -- genetics
- Prodrugs -- pharmacokinetics
- Prostate-Specific Antigen -- blood
- Prostatic Neoplasms -- blood
- Thymidine Kinase -- genetics
- Virus Replication
- Virus Shedding
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Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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