Synthesis and structure-activity relationships of new arylpiperazines: para substitution with electron-withdrawing groups decrease binding to 5-HT(1A) and D(2A) receptors. [electronic resource]
Producer: 20030213Description: 503-10 p. digitalISSN:- 0223-5234
- 8-Hydroxy-2-(di-n-propylamino)tetralin -- pharmacology
- Animals
- Coumarins -- chemical synthesis
- Drug Design
- Electrons
- Fibroblasts
- Hippocampus -- drug effects
- Humans
- In Vitro Techniques
- Indicators and Reagents
- Mice
- Piperazines -- chemical synthesis
- Raclopride -- pharmacology
- Radioligand Assay
- Rats
- Rats, Sprague-Dawley
- Receptors, Dopamine D2 -- drug effects
- Receptors, Serotonin -- drug effects
- Receptors, Serotonin, 5-HT1
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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