Intracellular single-chain variable fragments directed to the Src homology 2 domains of Syk partially inhibit Fc epsilon RI signaling in the RBL-2H3 cell line. [electronic resource]
Producer: 20020927Description: 2274-83 p. digitalISSN:- 0022-1767
- Agammaglobulinaemia Tyrosine Kinase
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal -- biosynthesis
- Binding Sites, Antibody
- Calcium -- antagonists & inhibitors
- Enzyme Activation -- genetics
- Enzyme Precursors -- immunology
- Humans
- Immunoglobulin Variable Region -- biosynthesis
- Intracellular Fluid -- immunology
- Intracellular Signaling Peptides and Proteins
- Isoenzymes -- antagonists & inhibitors
- Molecular Sequence Data
- Phospholipase C gamma
- Phosphorylation
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Rats
- Receptors, IgE -- antagonists & inhibitors
- Signal Transduction -- genetics
- Syk Kinase
- Transfection
- Tumor Cells, Cultured -- immunology
- Type C Phospholipases -- antagonists & inhibitors
- Tyrosine -- antagonists & inhibitors
- src Homology Domains -- immunology
- src-Family Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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